Using Cardiac Troponin Levels to Determine Myocardial Damage: Cardiac troponins, proteins that regulate calcium-dependent interactions between myosin and actin, facilitate cardiac contraction and relaxation. These proteins have three forms: troponin C, troponin I, and troponin T. Troponin C is found in cardiac and skeletal muscle cells. Troponin I and troponin T are specific to cardiac muscle.Learn more about this at cardiovascular scanning.
Studies of patients with chest pain show that measurements of troponin I and troponin T levels may be more sensitive indicators of myocardial damage than measurements of creatine kinase levels. And measuring cardiac troponin blood levels may more specifically identify patients who are at increased risk for cardiac complications.
In one study of 1,404 patients with unstable angina and non-Q-wave myocardial infarctions (Mis), those with troponin I levels of 0.4 ng/ml or more had a significantly higher short-term risk of death. In another study, patients with lower troponin T levels had improved long-term outcomes. During the first 4 months of follow-up, the risk of an Ml or death increased with higher troponin T levels.